Beta-lactamase gene expression in a penicillin-resistant Bacillus anthracis strain.
نویسندگان
چکیده
Expression of the bla1 and bla2 genes in an archetypal Bacillus anthracis strain is insufficient for penicillin resistance. In a penicillin-resistant clinical isolate, both genes are highly transcribed, but bla1 is the major contributor to high-level resistance to ampicillin. Differential expression of the bla genes is dependent upon strain background.
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ورودعنوان ژورنال:
- Antimicrobial agents and chemotherapy
دوره 48 12 شماره
صفحات -
تاریخ انتشار 2004